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🔬ESMFold2: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub

Latent Space: The AI Engineer Podcast · 27 MAY 2026 · 70 min

Alex Rives, Head of Science at Biohub, discusses ESM-C, a fourth-generation protein language model that leverages the "Bitter Lesson" of scaling with massive metagenomic datasets to achieve unprecedented protein structure predicti…

Protein language modelsAI for biologyScaling lawsProtein structure predictionProtein designMechanistic interpretabilityMetagenomic sequencingAntibody designVirtual cell modelsOpen scienceData generation